TOP 10 Russian-made creams with peptides for the face, reviews

Definition of face cream with peptides

Peptides themselves are the simplest compounds of two or more amino acid residues. Proteins, the building blocks of cells, also belong to this family. The difference is that by peptides, as a rule, we mean oligopeptides - the number of units is no more than 20. And proteins include up to 90 or more amino acid residues and reach a diameter of up to 110 Da.

What is the significance of these substances in cosmetology?

It is known that it is impossible to introduce any large molecules of a hydrophilic substance through the horny barrier of the skin. Nothing can penetrate through the horny scales, and a molecule with a diameter of no more than 200 A can pass through the gaps between the scales. In some cases, using the potential difference, molecules up to 300 A in size can be introduced through the sweat ducts. However, when it comes to proteins or hygroscopic substances such as hyaluronic acid, this difference is insignificant.

Peptides of 2–10 amino acid residues are much more compact. Accordingly, even in the composition of a cream, they can penetrate the horn barrier and perform their function - to become food or retain water.

Effect of cream with peptides.

Peptides, both synthetic and artificial, are absolutely safe, since, in essence, they are “blanks” for proteins. These substances do not cause allergies.

Cream with peptides is a very effective way to treat the skin. However, this is not a universal remedy and its use has its own characteristics.

• Any cream contains several types of peptides, usually reinforcing each other. Accordingly, the cosmetic product turns out to be narrowly targeted.
• Peptides are easily oxidized and destroyed, so the composition always contains stabilizers and preservatives. The cream is dosed in very small portions.

The shelf life of the cream with peptides after opening the jar is only 2–4 months. Then it becomes useless, since the substances are completely oxidized during this time.

• The cream has practically no effect on the condition of the upper layer of the skin, that is, the effect of rapid moisturizing is not observed. And to protect the skin you have to apply some other product.
• The base of the peptide composition is oily, so when caring for oily facial skin, you have to use it with caution.

Any cream contains several types of peptides

Where do Khavinson peptides come from in cells?

The protein that was synthesized in the cell does its job and then is destroyed. With the help of peptidase enzymes, it is “cut” into fragments. Some of them leave the body through the excretory system. And the other part is fragmented. Some protein fragments contain stretches of amino acids connected in a certain way. These are the peptide bioregulators that Khavinson discovered.

DNA activation

The bioregulator strictly corresponds to a specific section of the DNA molecule. It maps to this area, like a magnetic key that signals the magnetic lock to open the door. The DNA molecule unwinds, information is read from it, and cheat sheet matrices (RNA) are built, according to which the protein will be synthesized - the same one that was utilized before.

Accordingly, bioregulatory peptides are formed from protein, but without them the synthesis of the same protein is impossible.

Mechanism of action of pharmaceutical peptide drugs

From the point of view of cosmetologists, oligopeptides have a number of advantages compared to proteins or amino acids. The first ones are too large and no one will be able to insert them through the skin. The latter are too simple and cannot have a significant impact. Peptides can be absorbed by the skin and are quite complex. Therefore, their effects on the skin can be accurately differentiated and measured.

The concept of regulating aging processes with the help of peptides was developed in the 70s at the Laboratory of Bioregulation of the Military Medical Academy named after. S. M. Kirov. It is based on the theory that aging is a chronic process extended over time. The introduction of regulatory peptides leads to the activation of certain synthesis processes, thereby anticipating skin aging and stimulating the growth of new cells.

The general mechanism of action of peptides comes down to this role. They act not so much as an active substance, but as a signal of the need for the synthesis of one or another component.

Peptides are selective. Each of them acts according to its own “scheme”, that is, it irritates certain cell receptors. At the same time, the latter produce certain substances, as if they received this signal naturally.

For example, palmitoyl tripeptide-5 activates the formation of collagen and mucopolysaccharides, and these substances ensure restoration of elasticity. Matrixyl also serves as an activator of fibroblasts. But argireline is often compared to botulinum toxin, since it is a neurotransmitter. This substance prevents overstrain of small muscles, which helps soften and even remove expression lines. But unlike Botox, the peptide does not cause a mask effect.

Peptides can be administered either through the skin or by injection, and even taken in tablet form. Moreover, tablets and external agents are considered the most effective.

Cosmetics of the future: what are peptides

Since the beginning of the last century, “protein” cosmetics have been under the close attention of both developers and consumers, who prefer to know what exactly is in the next bright jar, and why this particular substance should help them keep their skin in good shape. You yourself probably know what collagen, keratin, elastin are and how often they are included in serums and creams. All these are squirrels, but of the “old generation”.

Another thing is peptides! Unlike other protein compounds, they have:

• simple structure - 2 or more chains of amino acids held together by a peptide bond (other proteins may contain 50 or more amino acids);
• miniature dimensions about 1 nm;
• relative stability, that is, the ability not to change its properties under the influence of external factors.

  
  Due to their small size, peptides act more efficiently than other proteins

It is thanks to all of the above that peptides outperform heavy and large proteins in no time, penetrating into the deeper layers of the skin and reaching cells that are inaccessible to conventional cosmetic products. And then they begin their main task: they stimulate cells to divide, renew themselves and resist the aging process. In addition, peptides improve intracellular metabolic processes, have a beneficial effect on skin microcirculation, and promote the absorption of oxygen and other substances necessary for the skin. With regular use of cosmetics containing peptides, cells are rejuvenated, the walls of blood vessels are strengthened, skin metabolism is normalized, and the skin itself becomes fresher, tighter, more elastic, getting rid of wrinkles and inflammation along the way.

Note: peptides penetrate into the deeper layers of the skin more easily if its surface has been pre-treated with a scrub.

Types of peptides

Cosmetologists distinguish 7 main groups of peptides used in creams from pharmacies or professional ones:

• Stimulants – like palmitoyl tetrapeptide-3. This substance is part of immunoglobulin G in combination with hexadecanoic acid. Stimulants have a strong anti-inflammatory and protective effect, activate the restoration of innate tissues and capillary intima. In addition, stimulants inhibit the activity of elastase and collagenase, enzymes that destroy collagen and elastin. Face cream with peptides of this group is used to quickly restore the skin, remove swelling and heal wounds.
• Stabilizers act as antioxidants, normalize the production of collagen and elastin, restore and maintain water balance. These include, for example, palmitoyl tripeptide-5, matrixyl TM. A cream with such substances is recognized as the best anti-aging face cream, because... promotes skin rejuvenation even at a very mature age.

• Blockers – argireline, acetyl ocapeptide-3 (better known under the commercial name “New snap-8”). Their role is to suppress nerve impulses that cause contraction of facial muscles. They act in different ways: they inhibit the corresponding neurotransmitter, reproduce the effect of a neuromuscular antidote, etc. In any case, such a cream reduces involuntary muscle tension, which, in turn, allows you to get rid of many facial wrinkles.
• Regulators – melanostatin-5TM. These kinds of substances suppress the production of melanin, which leads to noticeable lightening of the skin. This is one of the most powerful bleaches.
• Immunomodulators - like the already mentioned palmitoyl tetrapeptide-3. A cream with immunomodulators increases the skin's resistance to inflammation and irritants, as well as pathogenic microflora.
• Neurotransmitters – developed for the most sensitive skin. For example, rigin is a substance that inhibits the activity of interleukins, inflammatory mediators. This remedy reduces allergic reactions to external factors. Well, the absence of inflammation and irritation quickly puts delicate skin in order.
• Improving microcirculation - palmitoyl tripeptide-5, for example. It stimulates the regeneration of not only the skin, but also connective tissue and vascular walls. And with improved microcirculation, swelling automatically decreases and dark spots disappear.

Peptide creams can be used at any age. However, the indication for their use is, of course, age-related changes. For young beauties, the cream will be useful only if the skin is highly sensitive and prone to allergies.

Why you need to take peptide bioregulators

Even under ideal conditions, a healthy body, using internal reserves, replenishes the peptide deficiency by only 90%, and receives the remaining 10% from food. The problem begins at the moment when stress factors begin to affect the body:

• sedentary work;
• stuffy rooms;
• poor nutrition;
• bad environment, etc.

Under their influence, organs and tissues gradually wear out and they no longer have enough peptides that come with food. In this case, peptide drugs come to the rescue and temporarily fill this deficiency.

In the future, when the tissue produces the required amount of necessary proteins, its function is normalized. But if the body continues to be subjected to stress as before, the functioning of organs and tissues will again fail, and they will again need support.

How to use it correctly

Cosmetics of this kind are not considered medicinal, and peptides, despite their effectiveness, are not biologically active substances in the full sense of the word. That is, there are no restrictions on use - in courses, at certain intervals, there are no.

The cream, of course, includes not only peptides. However, additional ingredients are rarely active. Rather, these are substances that allow the product to be used by owners of different skin types. So, for oily skin, it is worth choosing a product with the lightest possible structure, and for dry skin, an option containing oils like olive or grape.

Recommendations for using cream with peptides are extremely simple:

• Peptides do not accumulate in the dermis layer, so a visible effect is possible only with regular use. As a rule, the cream is applied twice a day.
• To enhance the effect of the composition, you should resort to scrubs and peels as often as possible: they free the skin from dead horny scales. The fact is that the particles ready to peel off change their arrangement, and, therefore, prevent the penetration of peptides, since they block the gaps between the scales.

Find out which scrubs are best for oily faces in this material.

• You need to check the expiration date. When opened, the product produces an effect only for 2–4 months.
• For better care, especially for dry skin, it is recommended to use combined cosmetics, such as peptide-placental cream.

Peptide-placental cream average cost is 350 rubles.

Peptides do not cause allergies, but other components may be allergens. A skin test is necessary.

Types and classification of peptide bioregulators

There are 38 peptide bioregulators:

• 21 natural - animal raw materials are used for production, since all mammals have the same peptide bioregulators.
• 17 artificial - they are made from amino acids isolated from plants. Artificial peptide bioregulators are shortened copies of the main peptide that is included in the extract. Their effect is not as long-lasting as natural ones, but is achieved faster. This happens because the molecules are shorter and their concentration is much higher. According to Professor Khavinson, artificial peptides will become indispensable when humanity experiences a shortage of natural ones.

Preparations with peptide bioregulators can be divided into 3 groups:

• Cytomaxes are natural Khavinson peptides. For each organ there is a separate drug in capsules. Some of them are in the form of drops under the tongue - the “Lingval” series. There are also peptide complexes in solution for cutaneous use. Each such complex contains peptides for a specific group of organs.
• Cytogens are artificial Khavinson peptides in capsules. Each preparation contains peptides for one specific organ.
• Revilab are peptide complexes containing up to 4 artificial peptides from different organs. There are two types: Revilab SL - drops under the tongue, and Revilab ML - capsules.

Review of the TOP good peptide products: anti-aging, Korean

The leadership in the development and use of peptides belongs to Russian domestic manufacturers. European cosmetology pays more attention to fillers and moisturizing components. The Koreans should be considered Russia’s closest competitors: in recent years they have been actively developing this market. TOP pharmaceutical products with peptides and brief reviews of them.

• New Line from the Kora brand is a Russian manufacturer . In addition to the peptides palmitoyl trepetide-38, the cream includes soybean oil, glycerin, almond oil and cocoa. This is an excellent option for dry skin as it contains protecting and moisturizing oils. The product belongs to the category of night creams.
• "Evalar Laura" - anti-aging cream (stabilizing peptides included). Also contains glycerin and hyaluronic acid. The absence of oil allows it to be used by those with oily skin. However, the anti-aging effect is limited: the composition is intended to remove fine wrinkles, not deep ones.

Read more about anti-aging face cream with spf 50 peptides Laura here.

The effect of the cream can be enhanced with serum from the same series. Here the concentration of peptides is higher.

• DNS is a Belarusian product. The composition has a gel-like consistency; it is recommended to shake the bottle before use. Contains peptides from the blocking category, but in order for the Botox effect to be maintained, the composition must be used regularly. The gel is drawn up with a pipette, which prevents rapid oxidation.
• Mison peptide ampoule cream is a face cream produced by a Korean manufacturer. In addition to the high concentration of peptides, this includes extracts of medicinal herbs, which is what Korean cosmetics are famous for. The effect of application does not appear soon: you need to use the composition for at least a month.

We recommend that you familiarize yourself in more detail with the brands of Korean cosmetics at this address.

• Echoise is another Korean product. Includes peptides, soothing herbal extracts. The bottle has a convenient dispenser, which extends the “lifespan” of the cream: the dispenser does not allow oxygen to freely penetrate into the composition.

Cost 650 rubles.

• MeiYanQiong - includes peptides from a series of blockers. Visibly reduces expression lines on the eyelids and tightens the contour of the face. Also includes aloe vera, allantoin and plant collagen. Recommended for normal to oily skin, as, among other things, it tightens pores and reduces the number of acne.
• Sengara - the line includes 3 creams with slightly different compositions. To achieve maximum effect, it is recommended to use them alternately. The product with peptides 18 and 171 creates the best lifting effect, smoothing out fine wrinkles. Cream with peptides G8173 and 176 enhances microcirculation and promotes cell growth. At the final stage, a composition with secalosides is used, which helps stabilize the achieved result.

Find out more about the effects of face lifting cream here.

• Idealia, Vichy - includes a maximum of natural ingredients. The set with the cream includes special plates containing a concentrated compressed preparation. If the cream works on fine wrinkles, then the plates are applied to deep ones to smooth them out.

How Khavinsona peptides work and how to take them: we tell you in simple words

Bioregulators affect only the organ from which they were isolated. For example, Endoluten will act on the pineal gland, and Visoluten on the eyes. Therefore, doctors can prescribe a course of several drugs with different peptides in their composition. But experts do not recommend taking more than five bioregulators at the same time.

First of all, it is necessary to influence the mechanism of adaptation to stress and put the detoxification system in order. Therefore, we recommend starting therapy with drugs to restore the neuroendocrine, immune, vascular and nervous systems, and then normalize the functioning of other systems and organs with the help of local peptides: liver, cartilage, blood vessels, etc.

Peptide drugs have a cumulative effect - each subsequent course will be more effective than the previous one. After a 1-3 month course of peptides, they last for another six months. Therefore, in order to maintain organ functioning at the proper level, it is advisable to take two courses of peptide bioregulators per year.

Peptide bioregulators are compatible not only with each other, but also with traditional medicines. Thanks to their use, it is possible to minimize the dosage of the main medicinal drug - of course, after examination and consultation with the attending physician.

Peptides and expression lines

In cosmetology, preparations are used that contain substances aimed at smoothing wrinkles in the facial area, which smoothes out most of the external imperfections. The mechanism of action has been tested and studied - many doctors use it in practice when treating patients. There is a list of contraindications for peptides in cosmetology, which are not recommended for use in case of individual sensitivity to the components. This leads to disruption of facial functions, as well as external changes.

Who is peptide therapy suitable for?

The procedure involves the use of native methods that are common in cosmetology. They are responsible for restoring and launching natural healing and cell rejuvenation. They become more resistant to the negative influences that go through their life period. Additionally, complexes are used that make cells resistant to ultraviolet radiation and other influences.

According to reviews, peptides in facial cosmetology accumulate. It is important to pause for several months between different procedures to allow the skin to rest and recover.

Peptides are responsible for most of the internal processes and also control the condition of the human body. There are various drugs and medicines, the choice of which is trusted to specialists who have knowledge. It is important to consider what peptides are combined with in cosmetics. This will allow you to select a complex to suit the requirements of each patient.