Everything you wanted to know about Neuronox, but were afraid to ask!

Neuronox is an affordable drug based on botulinum toxin type A. The drug is classified as a myelorelaxant. Available in powder form for diluting the solution.

The drug is administered intramuscularly. Used to eliminate aesthetic problems and treat hyperhidrosis.

A little about the action of the active substance:

• Not detected in the blood at a therapeutic dose.
• The clinical effect begins to appear after a few days when using the recommended dose.
• The therapeutic effect lasts from three months to six months. The duration of the drug depends on the characteristics of the body.
• The restoration of the transmission of nerve impulses occurs gradually.

Indications for therapy:

• Patients over 18 years of age with blepharospasm.
• Children with cerebral palsy over two years of age who have foot deformities.

Indications in cosmetology:

• Women under 65 years of age who want to get rid of deep eyebrow wrinkles.
• Wrinkles in the forehead, décolleté and around the eyes.
• Hyperhidrosis - increased sweating.

The drug has a number of contraindications:

• Allergy to active substances.
• Drug treatment.
• Pregnancy and lactation period.
• Age up to 18 years.
• Acute infectious diseases.

Note. Neuronox administration is carried out only by a specialist. The doctor prescribes the dosage of the drug depending on the procedure. The injection is injected into the problem area. Sometimes an analgesic is used.

What it is?

Reference. Neuronox is a muscle relaxant that is produced in South Korea by the pharmaceutical company Medytox Inc. The drug is made on the basis of botulinum toxin type A, which has undergone a deep degree of purification and stabilization with hemagglutinin and proteins.

Each molecule of the neurotoxin complex weighs 900 kDa, which prevents its movement into surrounding tissues. The drug is available in the form of a dry white powder, packaged in glass bottles of 50, 100 and 200 units.

The safety of Neuronox has been proven by numerous clinical trials and experience of practical use exceeding 10 years.
The official distributor of the drug in Russia is New Line Cosmetology (NLC). The drug is used to fill small expression wrinkles in the face, neck and décolleté, as well as to change the contour of the lips. It is worth noting that we are talking about a change in shape, not volume - it causes temporary paralysis of the orbicularis oris muscle, which makes the lips less wrinkled and the line smoother. Neuronox injections also help get rid of excessive sweating in the feet, palms and armpits. Read about other Korean-made botulinum toxin preparations here.

Advantages

• The cost is lower than that of analogues, without sacrificing quality.
• Safety and low likelihood of side effects.
• The effect lasts from 5 to 7 months, depending on the individual characteristics of the body.
• Practical and convenient packaging.

Flaws

1. Prohibited for use under 18 years of age.
2. Not suitable for people with individual intolerance to the components.

Comparison with other drugs containing botulinum toxin

Comparative list of botulinum toxin composition:

• Activity units - display the dosage of drugs, where one dosage unit is equal to the average lethal dose for medium-sized laboratory mice.
• Molecular mass - the smaller the element size, the higher the diffusion of the injected drug, and accordingly, the larger area will be involved by injection.
  Important! In the hands of an inexperienced cosmetologist, this can lead to side effects and paralysis of the muscles around the treatment area. However, if the procedure is performed correctly, the effect will come quickly and will be noticeable immediately.
• Albumin is a protein component that stabilizes the effect of the substance. The more of it there is in the injection drug, the milder its effect.
• Excipients also have a softening and stabilizing effect on the diffusion and dynamics of the drug.

You will find a comparative analysis of drugs such as Botox, Dysport and Xeomin in a separate article.

On the pages of our website you will find a detailed description of such drugs based on botulinum toxin:

• Japanese cosmetology novelty - Refinex.
• Product from the USA Botox Allergan.

Do they have any effect?

Until the 2000s, the actual mechanism of action and effectiveness of nootropics was not particularly studied. Doctors prescribed them, and people drank them. There was a myth circulating among medical students that a month-long course of nootropics before exams improves memorization of the material, and to be sure, you need to inject it into a muscle or vein.

Now the proof of the drug’s effectiveness is not the doctor’s word, but research data. There must be at least three thousand participants, and they must be divided into at least two groups, one of which is a control group with a placebo. At the same time, neither the doctor nor the patient knows what each of the subjects is drinking - medicine or a “dummy”.

Nootropic drugs have been little studied, and studies of their effectiveness are inadequate. Either there are too few people, or the criteria are unclear. For example, they estimate the number of test points only after treatment - they apparently forgot before treatment. The American FDA, in principle, does not consider nootropics to be drugs - in the USA they are sold as dietary supplements.

“Everyone knows that nootropics are drugs without proven effectiveness. But they continue to be used, says Varvara Khaletskaya. — There are statistics, there are international protocols that help the doctor. But at the same time, each doctor’s personal experience remains with a wide range: from “they are useless” to “they are effective in many patients.”

The fact is that there is a rare exception: piracetam improves cognitive function in people with severe dementia, according to an assessment of 19 high-quality studies. But with a traumatic brain injury or mild dementia, piracetam will no longer help. Moreover, it is useless for healthy people who want to follow the path of Eddie Morra from the film “Dark Areas” and become a megabrain. Therefore, if biohacking experiments with Mexidol seem to be effective, it is only due to self-persuasion.

Indications and contraindications

Indications:

1. 
   Age and expression wrinkles around the eyes.

2. Mimic longitudinal wrinkles on the forehead.
3. Interbrow fold.
4. Crow's feet in the corners of the eyes.
5. Nasolabial fold.
6. Drooping eyelids and drooping corners of the eyebrows.
7. Wrinkles in the décolleté area.
8. Increased sweating.

Contraindications:

• Pregnancy and lactation period.
• Individual intolerance or hypersensitivity to the toxin.
• A course of treatment with antibiotic drugs.
• Age under 18 years.

Treatment of hyperhidrosis

Hyperhidrosis, or excessive sweating, is a delicate and very unpleasant problem. Excessive sweat production on the palms, feet and armpits, less often on the back, face and other parts of the body brings discomfort in everyday life. Of course, first you need to find out the real cause of hyperhidrosis before treatment; these could be hormonal disorders, features of the body’s nervous system. Dysport is an effective way to combat hyperhidrosis. The neurotoxin blocks signals to the nerve that stimulate sweating, as a result, the sweat glands practically stop producing secretions. This method of treating hyperhidrosis significantly improves the patient’s quality of life and allows one to get rid of uncertainty and anxiety due to increased sweating.

Are there any contraindications for its administration?

Yes, I have. Among them:

• Pregnancy
• Lactation and feeding period
• Presence of acute infectious diseases
• Oncological diseases
• Inflammatory processes in the area of ​​influence
• Bleeding disorders, taking anticoagulants
• Various decompensated states of organs and systems.

Attention: before administering botulinum toxin, a consultation with a specialist is required.

If you are in doubt, be sure to report your ailments - this will allow you to avoid complications and get the most effective result.

How is the procedure performed? Will I experience pain?

First, the specialist asks you about the desired result, examines problem areas, gives recommendations, talks about contraindications, the procedure itself and post-procedure care. The patient is then seated in a chair in a semi-recumbent position. Typically, Dysport injections are virtually painless and feel like a mosquito bite. In case of special sensitivity, a specialist may use a local anesthetic cream.

Cost of the procedure

On a note. Only a cosmetologist who has documents confirming his medical education and certificates of special training in working with botulinum toxins type A can purchase the drug.

On average, the price per bottle varies from 5,000 to 8,000 rubles.

The cost of the procedure depends on the injection area:

• Forehead - from 2000 to 8000 rubles.
• The space between the eyebrows, the bridge of the nose – from 3500 to 9000 rubles.
• Nose, nasolabial folds – from 800 to 1500 rubles.
• Lip contour from 800 to 1500 rub.
• Elimination of wrinkles on the neck - from 16,000 to 25,000 rubles.
• The area around the eyes – from 3000 to 7000 rubles.

When is it time to inject botulinum toxin?

It all depends on the individual characteristics of the patient. It is used:

• from 18 to 30-33 years - for the correction of early facial wrinkles and creases. For example, if you constantly frown and have a crease between your eyebrows, the drug will not only remove it, but also make you wean yourself from a stern facial expression
• from 30-33 to 60 years, botulinum therapy is successfully used to correct various age-related changes
• after 60 years, botulinum toxin must be used carefully, on the advice of a specialist: you need to remember that botulinum toxin can smooth out muscles, but it cannot remove excess skin

How is the procedure carried out in the salon?

Neuronox injections do not require special pre-procedural preparation from the patient. However, a week before the injections, you need to stop taking antibiotic drugs, as they enhance the effect of the toxin and can provoke the development of side effects.

Immediately before the start of the procedure, the cosmetologist questions the patient about the presence of allergic reactions to the components of the drug and, using a special marker, marks the points for introducing the substance. For injection, a solution with a 0.9% concentration is prepared based on sodium chloride.

The prepared solution can be stored for no more than 4 hours, and immediately after the procedure it must be deactivated with a 1% sodium hydrochloride solution.

Botox injections are a fairly painful procedure. Therefore, the doctor may suggest the use of a special anesthetic gel. In order for the analgesic to take effect, you need to wait 30 to 50 minutes.

I received botulinum toxin injections. What do I need to know about post-procedure care?

• Do not touch the injection sites, massage them, apply compresses, etc.
• You can’t lie down for several hours, take analgesics and antibiotics, or exercise
• It is recommended to avoid drinking alcohol and overheating for a week after the procedure
• If you want the effect of botulinum therapy to last as long as possible, for 6 months you will need to minimize everything that stimulates blood circulation in the treated areas: sauna, physiotherapy

Result

The first changes will be noticeable after 3 days. The final result will be visible after 2 weeks. The procedure can be repeated, if necessary, after 10 months.

Side effects

• Swelling or hematomas in the injection area. As a rule, they go away on their own after 2-4 days.
• Asymmetry of facial features, hypertonicity of the upper eyelid.
• Dryness and burning of the eyeball.
• Migraines, headaches as a temporary reaction of the body to the drug.

Preparing for botulinum toxin injections

The day before the injection you should not drink alcohol

– it may increase the risk of bruising and hematomas.
It is advisable to stop taking antibiotics and anticoagulants (aspirin, cardiomagnyl and other blood thinning drugs)
. In addition, on the day of the injection,
you should not tilt your head for a long time
. If the head is lowered for a long time, blood circulation in the facial area will increase and the drug may not be distributed correctly. For this reason, it is not recommended, for example, to attend massage sessions, during which you will have to lie face down, iron, vacuum and wash the floor (due to the need to keep your head tilted) and buy shoes (fitting is also usually associated with constant bending ).

Can it be used in combination with other drugs?

Cosmetologists recommend combining Neuronox injections with mesotherapy injections, thread lifting or contouring. The interval between procedures should be at least two weeks. Botox immobilizes the facial muscles, allowing the drugs to be distributed better under the skin. The effects of procedures performed against the background of Botox become more noticeable.

Can it be combined with alcohol?

As mentioned earlier, alcoholic beverages are prohibited for patients during the period of preparation for injections, as well as 4 days after the procedure.

Botulinum toxin is a powerful beauty weapon!

Dysport and Neuronox are botulinum toxin preparations,

Botox analogues
(Botox is not used in the Republic of Belarus, but Dysport and Neuronox are officially permitted in Minsk and the Republic of Belarus)
.

Starting from about 25 years of age, the body of any person begins to age. The skin of the face and neck loses elasticity, wrinkles, creases and folds appear. Expression wrinkles may appear earlier in the most emotional patients, as well as due to a special facial structure or genetics.

But if you have an irresistible desire to look better, if you want to remain attractive longer and achieve confidence in your career and personal life, and massages, masks and other skincare treatments no longer help - botulinum toxin (Dysport, Neuronox) is just for you!