Injection of hyaluronic acid into the face: cost, types, contraindications

The effect of hyaluronic injections in the face

Contour plastic surgery with hyaluronic acid is a procedure during which a cosmetologist injects filler under a wrinkle or skin fold and fills the insufficient volume with the drug. This allows you to model your appearance, correct facial asymmetry, smooth out wrinkles, scars, scars, moisturize and rejuvenate the skin.

Hyaluronic facial injections are also popular among women who want to increase the size and volume of their lips.

To prevent pain and discomfort, half an hour before the injections, the cosmetologist applies an anesthetic cream to the affected area.

The result of contouring with hyaluronic acid is noticeable immediately after injection correction, but the final assessment of the result can be made in a couple of days, after the slight swelling in the injection area has subsided.

Why don’t all external products with hyaluronic acid work?

Hyaluronic acid belongs to the class of polysaccharides, or more precisely glycosaminoglycans. It consists of repeating fragments (Fig. 3), which are usually called disaccharide units. Normally, one hyaluronic acid molecule contains up to 25 thousand of these repeating fragments. As a result, the molecule is a ribbon (Fig. 4), which is rolled into a loose tangled ball.

Hyaluronic acid molecules are large in size and molecular weight, and therefore they normally do not penetrate the skin - deeper than the cracks between dead epidermal cells. Therefore, some manufacturers use low molecular weight hyaluronic acid in their creams and serums, which has been artificially reduced to a size that allows it to penetrate the skin well.

Therefore, the size of HA molecules in skin products is very important! The size (mass) of hyaluronic acid molecules is measured in daltons (Da). A standard hyaluronic acid molecule has a mass of up to 25,000,000 Da. In some sources you may find mass notation in the form of kDa (kilo Dalton). So, for example, 25,000,000 Dalton = 25,000 kDa).

Low molecular weight hyaluronic acid –

Low molecular weight molecules are considered to be hyaluronic acid molecules with a chain size of less than 130,000 Daltons. Such molecules penetrate the difficult skin barrier much more easily. Having penetrated the dermal layer of the skin, such molecules absorb water from the inside (which penetrates the dermis through the walls of blood vessels). By binding and holding it, they saturate the dermis with moisture.

But even low molecular weight HA is heterogeneous. Different size chains have completely different effects. Therefore, the best manufacturers use low molecular weight HA in their products not of one size, but of different sizes...

• Chains weighing from 400 to 10,000 Daltons - they most contribute to angiogenesis, i.e. the appearance of many microvessels in the dermis. This leads to better blood supply to the skin, which means better saturation of it with oxygen, nutrients, and activation of metabolic processes in the skin.

• Chains weighing from 50,000 to 130,000 Daltons - this size of molecules leads to good saturation of the dermis with moisture, but this size of chains especially stimulates cell proliferation and migration, increases the activity of fibroblasts + the production of new collagen. The activity of keratinocytes also increases, which helps to increase the thickness of the epidermis and increase its hydrophobic properties (i.e., the thicker the epidermis, the less moisture will evaporate from the surface of the skin).

Important : studies have shown that HA chains weighing up to 1 million Daltons can pass through the skin. However, the same studies showed that HA chains weighing from 500,000 to 1,000,000 Daltons (they are already considered high molecular weight) partially cause the opposite effects. Although they saturate the dermis with moisture, they also suppress the proliferation of fibroblasts, collagen synthesis, and angiogenesis (24stoma.ru).

High molecular weight hyaluronic acid –

Molecules of hyaluronic acid with a chain size greater than 130,000 Daltons are considered high molecular weight. But that doesn't mean they don't work. High molecular weight hyaluronic acid forms a thin gel-like “polymer” film on the surface of the skin, which begins to very quickly absorb moisture from the air.

The formation of a gel-like film leads to the following effects:

• an increase in water content in the epidermal layer of the skin,
• an additional barrier appears for the evaporation of moisture from the skin surface,
• The polymer film allows the biologically active components included in the cosmetic product to contact the skin longer and more closely, which increases their absorption.

Important : the greater the molecular weight of the hyaluronic acid used (we remind you that its maximum weight = 25,000,000 Daltons), the higher the effectiveness and duration of action of such a gel-like film.

Who is recommended for facial hyaluronic acid injections?

Contour plastic surgery with hyaluronic acid is recommended for patients with the following problems:

• deep nasolabial folds and “crow’s feet” (wrinkles in the corners of the eyes);
• horizontal and vertical wrinkles on the forehead;
• sagging cheekbones, sunken cheeks;
• loss of elasticity and firmness of facial skin;
• asymmetry of facial features;
• irregular chin shape;
• unclear lip contours, their inadequate volume;
• signs of photoaging of the epidermis;
• dry and dehydrated facial skin.

Contour plastic surgery with hyaluronic acid fillers is the fastest, most delicate and highly effective way to eliminate the above-mentioned shortcomings, which negatively affect not only the patient’s appearance, but also his internal state, causing the development of numerous complexes.

CONCLUSIONS on choosing skin products -

Thus, HA molecules of different masses work completely differently. This can influence the choice of skin care products, depending on what you expect from using such products.

• Products with low molecular weight hyaluronic acid will work from the inside, penetrating the dermal layer of the skin, increasing its water content, which leads to an increase in the degree of hydration of collagen and elastin and an increase in their elasticity.
  They also activate the function of fibroblasts and keratinocytes, increase collagen production, increase metabolic processes in the skin, and stimulate angiogenesis. Studies have shown that products with HA molecules from 50,000 to 130,000 Daltons are better than others in helping to restore skin elasticity. Just keep in mind that HA molecules are destroyed in the body over time: from less than a day to 2 days. Therefore, these products must be used constantly, otherwise you will slip back to the original skin condition. Moreover, the smaller the size of HA molecules, the faster they are destroyed by macrophages.

• Products with high molecular weight hyaluronic acid - the size of the HA molecules in such products should be at least 1,000,000 Daltons (and this is the worst option).
  In the best case, the molecules should have a maximum size, i.e. approaching 25,000,000 Daltons. Keep in mind that such products can, on the contrary, dry out your skin if the surrounding air is not sufficiently humidified, i.e. dry In this case, the gel-like film will tend to absorb water even from the surface layer of the skin. These products allow you to quickly moisturize and improve the condition of the most superficial layer of skin (epidermis). You shouldn’t count on an increase in moisture in the dermis and an increase in skin elasticity. The effectiveness of such products will be much higher if, in addition to HA, they contain ceramides (unsaturated fatty acids), which also prevent the evaporation of moisture from the surface of the skin.

Facial contouring with hyaluronic acid: types and areas of treatment

The popularity of facial contouring is explained by the absence of complications and the immediate effect - rejuvenation and renewal of the face.

Hyaluronic acid injections for the face are performed on the following areas:

• on the lips – the procedure is carried out to increase the size of the lips, give them volume, and correct the contour. Beauty injections into the lips help eliminate wrinkles around the mouth, scars after injuries and surgical interventions, as well as solve the problem of drooping corners and asymmetry of the lips;
• on the nasolabial folds - injections of hyaluronic acid into the face eliminate networks of facial wrinkles and age-related skin creases in the area connecting the wings of the nose and the chin;
• on the cheekbones – correct congenital or acquired insufficient expression of the zygomatic arches by increasing them;
• chin – hyaluronic injections for the face help change the size and shape of the chin, which ensures its flawless and harmonious appearance;
• on the forehead - eliminate deep vertical and horizontal expression wrinkles, the interbrow fold;
• on the nose – hyaluronic injections for the face correct the shape of the nose, improve its proportions: eliminate asymmetry, straighten the bridge of the nose, correct the tip and wings;
• on the ears - they replenish the volume of the earlobes when they sag, thereby rejuvenating them, eliminating traces of injuries, sprains after wearing massive earrings;
• in the periorbital area – smooth out the relief of the skin around the eyes, successfully replacing surgical blepharoplasty;
• on the body – contouring with hyaluronic acid allows you to visually model your figure and mask aesthetic skin imperfections on different parts of the body – cellulite pits, atrophic scars, protruding blood vessels of the arms, etc.
• on the genitals - contouring of intimate areas with hyaluronic acid improves their aesthetic appearance and functionality. It is relevant for ptosis and laxity of the labia, birth and postoperative defects, insufficient accessibility of the clitoris, its severe hypoplasia, hypermobility of the urethra and other pathologies.

The above areas are the most popular among patients who undergo beauty injections. Hyaluronic acid injected into problem areas allows you to correct any defect and restore your former aesthetic appeal.

Expected effect of mesotherapy with hyaluronic acid

The active launch of the processes of restoration and hydration of the skin occurs during mesotherapy sessions, acting from the inside. As a result of the procedure, we observe visible rejuvenation and improvement of complexion: skin elasticity increases, and the oval becomes clearer.

Mesotherapy is rightfully considered the most popular method of rejuvenation of both female and male faces, because the effect of the procedure is amazing. The use of mesotherapy cocktails (several drugs at once) has become quite common, which help cope with a variety of problems with the appearance and health of the skin.

With the help of mesotherapy, it is possible to effectively solve problems to improve the skin of the face, figure and hair. For example, the procedure helps to cope with wrinkles, pigmentation, rosacea, acne, alopecia, seborrhea, cellulite and stretch marks. If there are no pronounced imperfections, mesotherapy can be used for prevention.

During the procedure, the effect occurs not only locally, but also comprehensively: tissue nutrition is stimulated, blood circulation is enhanced, and the skin is vitaminized. The overall appearance becomes more youthful, radiant and toned. Noticeably less fat deposits, orange peel skin and stretch marks.

The following factors influence the result of the procedure:

• the state of the client’s body;
• skin features;
• age-related changes and their degree;
• meso cocktail quality;
• qualification of a doctor or cosmetologist who does mesotherapy.

If therapy is carried out by an experienced specialist, it is possible to eliminate appearance problems that bother the client. When describing the technique, cosmetologists assure of its effectiveness. The procedure helps:

• get rid of shallow wrinkles;
• smooth out old expression wrinkles;
• moisturize the skin;
• overcome dryness;
• reduce the shine of oily skin by regulating the secretion of subcutaneous sebum;
• dissolve acne scars;
• restore elasticity;
• tighten the oval of the face;
• eliminate double chin;
• remove spider veins;
• fight acne;
• improve complexion;
• eliminate scars and scars.

When administering injections with mesococktail, rehabilitation after various surgical operations on the face is accelerated. Grinding or peeling also requires further restoration of the skin, the procedure does an excellent job with this too. A clear difference between photos taken before and after mesotherapy with hyaluronic acid can be seen below.

Hyaluronic injections for the face: procedure progress

First of all, the cosmetologist needs to talk with the patient and find out what result he expects from contour plastic surgery. The doctor selects the most suitable filler and outlines the injection area.

Immediately before the procedure, the correction area is thoroughly cleaned and disinfected, and a cream with an anesthetic effect is applied to the skin.

The filler is injected subcutaneously using a syringe or a special cannula. Injections of hyaluronic acid for the face in various areas require the use of certain techniques:

• To correct wrinkles, liquid fillers are injected under the skin, linear filling or a delicate technique is used - blanching (suitable for eliminating wrinkles in the periorbital area);
• To give cheekbones, chin and other areas additional volume, softlifting with high-density fillers is used.

The average duration of injection correction is 30-60 minutes. After injections, slight swelling and redness of the skin may appear. These symptoms disappear on their own after a couple of hours.

Who should not receive hyaluronic acid injections in the face?

Contouring with hyaluronic acid fillers is contraindicated in the presence of the following conditions:

• tendency to form keloid and hypertrophic scars;
• hemophilia;
• viral and fungal dermatological diseases;
• diabetes mellitus type I and II;
• hemocoagulation disorders;
• chronic diseases in the acute stage.

Hyaluronic injections for the face should not be performed on pregnant and lactating women, or during menstruation.

What is hyaluronic acid obtained from?

The first hyaluronic acid-based products were created in the 1980s. Hyaluronic acid was originally obtained from cockscombs, so these fillers contained a mixture of poultry proteins. Currently, hyaluronic acid is obtained by biofermentation of Streptococcus equi and Bacillus Subtilis bacteria, strains that are non-pathogenic to humans.

Due to the fact that hyaluronic acid is the same substance for all organisms and species, its biocompatibility eliminates the need for preliminary testing, sensitivity testing and the body's response to its use. As medicine develops, we get an increasingly ideal product.

Hyaluronic acid for the face (injections): cost at the Sharm Gold clinic

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Frequently Asked Questions About Hyaluronic Acid Injections

Injection facial correction is practically painless thanks to the use of topical anesthesia and the use of a very thin needle to administer the drug.

In recent years, the demand for hyaluronic acid injections for the face has increased sharply. The price in Moscow for these procedures is quite affordable for everyone, since the doctor can select a filler taking into account the patient’s financial capabilities.

The result of the procedure lasts from 1 to 2 years. If desired, injections of hyaluronic acid into the face can be repeated.

There is no risk of developing negative consequences of the procedure. Over time, hyaluronic acid “resolves” in tissues on its own.

No special preparation is required for the procedure. A few days before the injections, it is enough to refrain from alcohol, smoking, caffeine-containing drinks, avoid taking anticoagulants, and visiting beaches and solariums.

Cream with hyaluronic acid: reviews, how to choose

Many consumers know what an excellent moisturizing effect hyaluronic acid has, and therefore they look for this particular ingredient in creams.
More and more brands are advertising hyaluronic acid in their creams, but if you read their ingredients on the label, it turns out that they are listed at the very bottom of the list. This means that the proportion of hyaluronic acid there is extremely small. Recommended concentrations of hyaluronic acid –

• conventional skin care products 0.05-0.4%,
• highly moisturizing products and anti-aging cosmetics – 0.5-1.5%.

Do not buy products with hyaluronic acid where the percentage of its content is not indicated! In addition, it should be indicated whether the product contains hyaluronic acid itself, or its salt – sodium hyaluronate.

Recommended sizes of HA molecules in skin products - ideally, if the manufacturer indicates the molecular weight of hyaluronic acid molecules in the composition of their product. Some (without quantitative indicators), which does not inspire confidence. Serums should only be made from low molecular weight HA with a molecular size of up to 130,000 Daltons.

In cream products, the choice of HA molecular size will depend on what effects you are expecting -

• If you are more interested in increasing skin elasticity, then in this case the size and mass of HA molecules should be from 50,000 to 130,000 Daltons.
• If there is a rapid obvious improvement in the hydration and appearance of only the upper layer of the skin, then the mass of HA molecules should be as large as possible, but not less than 1,000,000 Daltons. We described in detail why this is so at the beginning of the article. And, by the way, such funds will be much cheaper than the first ones.
• There are products that contain a combination of both low molecular weight and high molecular weight HA. This option will probably be preferable.

Attention to additional components - it is better to refrain from creams that contain: fragrances, alcohol, natural oil essences (they reduce the effect or destroy hyaluronic acid molecules). But vitamins C, E and B5, on the contrary, enhance its effect, and therefore it is very good if they are included in the cream. It is very good if the cream contains ceramides (unsaturated fatty acids), which also greatly moisturize the epidermis and prevent the evaporation of moisture from the surface of the skin.

Is it possible to add a solution of hyaluronic acid from ampoules to a regular cream?

If you find an excellent moisturizer that suits your skin, but it does not contain hyaluronic acid, you can buy it at the pharmacy in the form of ampoules and simply add it to your cream. In this case, hyaluronic acid will have a large mass of molecules and will not penetrate the skin. But, as we have already said: working on the surface of the skin, it forms a gel-like polymer film.

This protective film remains on the skin for a long time; after application, it begins to absorb water from the air, which leads: firstly, to the saturation of the surface layer of the skin with moisture, and secondly, to protection against moisture evaporation from the surface of the skin. Those. as we see, creams with both high and low molecular weight hyaluronic acid will work to moisturize the skin. They will just do it in different ways, and to different depths.

The mechanism of action of low molecular weight hyaluronic acid is completely different. Penetrating into the dermis, they absorb water there (coming from blood vessels), which leads to an increase in the moisture content in the dermal layer of the skin, and also affects fibroblasts, collagen, etc. there.

Hyaluronic acid or sodium hyaluronate in cream: which is better?

Sometimes you can read in the composition that the cream does not contain hyaluronic acid, but sodium hyaluronate. This may not be clear, so it requires a little clarification. Chemically, sodium hyaluronate is a salt derived from hyaluronic acid. It has a number of advantages over hyaluronic acid itself, although both of these components have good moisture-retaining properties.

The main difference between sodium hyaluronate is its molecular size. During the process of creating sodium hyaluronate, its molecular weight is reduced by removing lipids and nucleic acids, making the molecule much smaller than hyaluronic acid. This means that when applied topically, sodium hyaluronate molecules penetrate the skin more easily.