Composition and benefits
The formula of high-density biphasic universal filler Reneall 300 includes hyaluronic acid (2%) and butanediel diglycedyl ether (BDDE - 4%). Thanks to its ability to retain moisture, HA helps recreate volume in the desired area. And BDDE is responsible for the intermolecular cross-linking of hyaluronic acid itself.
Reneall 300 is intended for the correction of deep wrinkles and folds, replenishment of small and large volumes of tissue and contour correction. In addition, the filler is used to smooth out nasolabial and labiomental folds, bio-reinforcement and oval of the face, to increase the volume of the chin and form the volume of the cheekbones and in injection rhinoplasty.
Reneall 300 filler is injected into the deep dermal layers (2.0-5.0 mm), subcutaneously and supraperiostally using a linear-retrograde bolus technique.
Reneall
It is believed that all hyaluronic fillers presented on the Russian market are divided into two groups: expensive European and cheap Chinese. However, for several years now, cosmetologists have been actively using Russian-made drugs, which have a very good price/quality ratio, to carry out volumetric correction of the face, body and hands.
Reneall (Renial) is a whole line of fillers and biorevitalizants based on hyaluronic acid, which have been available in our country since 2010. During this time, they have fully proven their safety and effectiveness, quite successfully competing with well-promoted Western brands.
What are these drugs? In what cases are they used? What are the differences from foreign analogues and how much will the procedure cost? TecRussia.ru examines all the main issues in detail:
↑ Who produces Reneall
- Filler developer – . It is part of the NMTC research holding, which specializes in the production and distribution of drugs based on hyaluronic acid (its products include Revi and Amalain fillers, elite cosmetics Dermastir, drugs for the treatment of cystitis and osteoarthritis).
- Direct production is carried out by the Limited Liability Company "SLS", whose technical facilities are located in Moscow, and equipment purchased in Germany. The supplier of raw materials is the South Korean company LG Life Sciences (produces the popular Yvoire filler).
- The drugs have been registered as medical products, hyaluronic biopolymers, and are approved for use in the Russian Federation (in the Roszdravnadzor register they are listed as “Riniall”, FSR 2010/07368).
↑ Composition and release form
The basis of Reneall fillers and biorevitalizants is hyaluronic acid (HA) of non-animal origin with a special two-level structure formed using special cross-links. It works like this:
- the release of HA molecules at the first level begins immediately after the injections and continues for 2-3 months, providing the main visual and therapeutic effect of the procedure;
- then, when these particles begin to naturally break down and be eliminated from the body, second-level molecules are released, which maintain the result for another 6-8 months.
In addition to HA, all preparations contain a standard base: purified water, sodium chloride (salt) and a buffer solution. Each package contains glass syringes with a volume of 1 and/or 2 ml, needles of the most suitable diameters and detailed instructions for use. The cardboard box is equipped with two stickers indicating the batch number, production date and expiration date.
↑ Line of drugs Reneall
Fillers (tissue implants). Their task is to fill the missing volume of soft tissues of the face or other treated area:
| Brand | Volume | Indications |
| 100 | 1 ml | Ideal for filling fine lines on the forehead, eyelids and around the mouth |
| 200 | 1 ml | Can be used to correct wrinkles of medium depth in the forehead and bridge of the nose, nasolabial folds. Suitable for insertion along the lip contour. |
| 300 | 1 ml, 2ml | Used to correct deep wrinkles, soft tissue defects, modeling facial volume, and also for lip augmentation. |
| Secret Life | 1 ml | Designed specifically for volumetric corrections of the intimate area: the shape and size of the labia majora and minora, enlargement of the glans penis, enlargement of the G-spot, clitoral mantle, etc. Injected into the middle layers of the dermis. |
| Pro Active | 2 ml | Another drug for intimate contouring, differs from Secret Life in its larger volume, the density of HA is the same (20 mg/ml), and is intended for injection into the deep layers of the dermis. |
Revitalizants. They are administered to generally improve the condition of the skin, increase its level of moisture, and accelerate metabolic processes:
| Brand | Volume | Indications |
| Revitalist | 1 ml, 2ml | Injected into the skin of the face, neck and décolleté. It has a prolonged effect, so it can be used at the end of a biorevitalization course to consolidate the effect obtained, and also once, to maintain a normal level of skin hydration between courses. |
| Body | 2 x 2ml | Designed for injection into various areas of the body. |
| Hand | 2 x 2ml | Combined complex (1 syringe of filler and 1 syringe of biorevitalizant) for rejuvenating the skin of the hands |
↑ How the procedure works
Injections are performed using local anesthesia. Depending on the location and depth of drug administration, a cream with an anesthetic is first applied to the skin, and less often, conduction anesthesia is used. In some cases, you can get by simply applying ice. The manufacturer strongly does not recommend infiltration anesthesia (lidocaine and similar injections), as it often leads to a change in the shape of the face, which can affect the correctness and symmetry of filler injection.
Next, the cosmetologist opens the Reneall package, always in the presence of the patient. The needle included in the kit is put on the syringe, after which the injection session itself is carried out: the drug is injected to the desired depth using the chosen technique (depending on the aesthetic problems being solved). After completing the manipulations, the doctor will disinfect the treated area and tell you about the necessary post-procedure restrictions - in particular, you will need to avoid tanning, physical activity and visiting the sauna for several days.
| Photos before and after contour plastic surgery with Renial preparations. Hand rejuvenation: | |
| Lip augmentation: | |
↑ Contraindications, complications, side effects
Reneall is not administered in the following cases:
- pregnancy and lactation;
- hypersensitivity to any of the components of the drug;
- acute infectious diseases;
- autoimmune and oncological diseases;
- herpes in the presence of fresh rashes on the skin;
- psoriasis;
- diabetes.
The main side effects are associated with microtraumas caused by punctures of the skin with a needle, and are typical for any injection procedures using any brand of drugs - redness, itching and slight soreness in the treated areas, which persist for several hours after the session. There were no specific complications or side effects associated specifically with Renial.
- Complications after contouring
- Papules after biorevitalization
Also, it is worth remembering that the hyaluronic acid contained in the preparation retains water. In this regard, in the first three to four days, significant swelling may remain in the chipped area (for more details, see the article “Swelling after hyaluronic acid fillers: what to do?”).
↑ How much does Renial cost? Current prices, analogues
The drug belongs to the middle price category, it will cost significantly less than elite European brands, but more expensive than the bulk of Chinese “economy class” products:
| Reneall fillers – average prices in Moscow (RUB): | |
| 100 | 10.414 |
| 200 | 10.707 |
| 300 | 11.066 |
| Revitalist | 18.500 |
| * all prices listed are synchronized with the TecRussia.ru price list database and are current as of the current date. | |
As for analogues, there are no significant differences between HA-based fillers; for example, Hyaluform, Surgiderm, Teosyal, etc. have the same properties. But Reneall Revitalist, which belongs to the “hydro reserve” group, differs from other biorevitalization drugs in its longer action. Only a few other brands provide a similar effect, for example, Restylane Vital and IAL System ACP.
Warning
Hyaluronic fillers are not recommended for use by pregnant or lactating women, patients under the age of eighteen, patients with autoimmune diseases, or people with individual intolerance to hyaluronic acid.
It should be taken into account that before using hyaluronic filler, the patient must inform the doctor about the presence of allergies, immune diseases or infections.
Hyaluronic acid injections should not be combined with any other aesthetic dermatology techniques, including laser therapy or chemical peels, if they were performed less than three weeks ago.
*Information about this drug is for reference only. *The online store FillerStore.ru offers only original Reneall products.
Reneall 100
Description:
Low Density Dermal Filler
Compound:
Cross-linked hyaluronic acid
HA concentration:
2% (20 mg/ml)
Indications:
- correction of mild and medium wrinkles (folds)
- replenishment of small and large volumes of tissue
- relief leveling
- contour correction
- increasing lip volume
Introduction area:
fine wrinkles in the forehead, eyebrow wrinkles, crow's feet, bio-reinforcement of the oval of the face; thin nasolabial folds, small purse-string wrinkles, lip commissures, correction of the contour and volume of the lips, small labio-mental wrinkles, volumetric plastic surgery of the dorsum of the hands; filling neck wrinkles, bio-reinforcement of décolleté, chin wrinkles
Insertion depth:
Superficial and middle layers of the dermis (0.5-1.5mm)
Effect Duration:
4-7 months
Release form:
1 spr. x 1 ml.; needles 2x27G
Reneall 200
Description:
Medium density dermal filler
Compound:
Cross-linked hyaluronic acid
HA concentration:
20 mg/ml
Indications:
- correction of moderate wrinkles (folds)
- replenishment of small and large volumes of tissue
- contour correction
Introduction area:
Pronounced wrinkles in the forehead, pronounced glabellar wrinkles, crow's feet, bio-reinforcement of the oval face, pronounced nasolabial folds, labio-mental folds, pronounced purse-string wrinkles, correction of the contour and volume of the lips, lip commissures, labiomental wrinkles, volume and wrinkles of the chin, injection rhinoplasty, replenishment of the deficit and volume of the midbuccal groove
Insertion depth:
Middle and deep layers of the dermis (from 2.0 mm)
Effect Duration:
8-12 months
Release form:
1 spr.x 1 ml / 1 spr.x 2 ml; needles 25G, 26G / 26G, 27G
Reneall 300
Description:
Medium density dermal filler
Compound:
Cross-linked hyaluronic acid
HA concentration:
20 mg/ml
Indications:
- bioreinforcement, correction of moderate and deep wrinkles
- replenishment of small and large volumes of tissue
Introduction area:
deep wrinkles in the forehead, deep glabellar wrinkles, injection rhinoplasty, bio-reinforcement of the facial oval, deep nasolabial folds, lip commissures, labiomental folds, chin wrinkles, chin volume, filling the midbuccal sulcus
Insertion depth:
Middle and deep layers of the dermis (from 2mm)
Effect Duration:
8-12 months
Release form:
2 spr. x 1 ml; needles 25G, 26G / 4x25G
Reneall Revitalizant
Description:
Hyaluronic gel for biorevitalization
Compound:
Hyaluronic acid
HA concentration:
20 mg/ml
Indications:
- age-related skin changes, dehydration of the dermis, finely wrinkled type of aging, skin with signs of photo- and chronoaging, decreased turgor and elasticity, aging skin of the face, neck and décolleté, pigmentation, dehydrated skin after tanning, solarium and exposure to low temperatures;
- dysfunction of the sebaceous glands; acne;
- alopecia;
- preparation for volumetric and contour plastic surgery, thread lifting;
- preparation and rehabilitation for plastic surgeries and medium and deep peels;
- prevention and correction of signs of aging
Introduction area:
face, neck, décolleté, scalp, lower leg, thighs and buttocks, shoulder and forearm, dorsum of hands and feet, anterior abdominal wall
Insertion depth:
Deep layers of the dermis (2.0-5.0mm), subcutaneous, supraperiosteal
Effect Duration:
4-5 months
Release form:
1 spr. x 2 ml. needles 2x30G
