The first signs of aging are directly related to a decrease in hyaluronic acid in the skin, the main component of the intercellular matrix. Hyaluronic acid is responsible for skin turgor and elasticity. Its decline can be natural (physiological) or premature (pathological). A premature decrease in hyaluronic acid in the skin is caused by active sun exposure, chronic intoxication (for example, smoking), stress, inadequate skin care, and some somatic diseases.
To restore the concentration of hyaluronic acid in the skin, biorevitalization is used - an injection method of introducing native hyaluronic acid. The main goal of biorevitalization is to slow down the aging process.
The Fidia company (Italy) is a pioneer in the development of the concept of biorevitalization and the production of preparations for dermatocosmetology. The following drugs have been developed for practical use: Ial-System and Ial-System ACP.
1. Ial System / Ial system is a sterile visco-elastic gel based on hyaluronic acid of biosynthetic origin with a concentration of 18 mg/ml. Available in syringes with a volume of 0.6 and 1.1 ml and is one of the safest drugs for intradermal administration, which is perfectly compatible with the skin.
2. Ial System ACP is a sterile gel based on hyaluronic acid with a mesh structure, obtained using the patented “auto-cross-link” technology with a concentration of 20 mg/ml. It is available in 1.0 ml syringes. When introduced into the dermis, the drug is broken down in 2 stages. At the first stage, it absorbs water and the crosslink is destroyed with the formation of hyaluronic acid chains. In the second stage, hyaluronic acid is destroyed by the enzyme hyaluronidase, resulting in the release of fragments of hyaluronic acid of various molecular weights. The drug restores the proliferative and functional activity of fibroblasts, normalizes microcirculation of the dermis and enhances antioxidant protection.
The effect of Ial System ACP will be more pronounced in well-moisturized tissues, therefore it can be used in basic programs after Ial-System / Ial systems or in the same procedure with it.
On what areas can Ial System be used?
Ial System / Ial systems can be used on absolutely any area of the skin that needs “restoration”. As a rule, exposed areas lose tone and elasticity the fastest: face, neck, décolleté, hands. They are the ones most often exposed to ultraviolet radiation.
Biorevitalization course Ial System
A) Patients are under 30 years of age.
The course is carried out to increase skin turgor in people who abuse tanning, to prevent photoaging, before traveling to hot countries and 2 weeks after returning, as well as to correct premature wrinkles in patients with dry skin with sudden weight loss. This group uses Ial System monotherapy.
B) Age from 30-45 years.
The course is carried out with the aim of increasing skin turgor and elasticity, restoring its adaptive properties. And also during the rehabilitation period after chemical peels, laser rejuvenation, phototherapy. The primary course includes 2 Ial-System procedures, after 2 weeks Ial-System ACP, a month later - the second Ial-System ACP procedure. Maintenance course - Ial System ACP or Ial System every 4-5 months.
B) Age after 45 years.
The course is carried out with the aim of replenishing the deficiency of hyaluronic acid in the dermis, stimulating fibroblasts, and restoring microcirculation. The primary course includes 2 Ial System procedures once every 2 weeks, after 2 weeks - Ial-System ACP, after a month - again Ial System ACP. Repeated course - injections of Ial System ACP are carried out at intervals of 3-4 months. In patients with dry skin, the scheme of simultaneous administration of two drugs once a month has proven itself to be effective.
Characteristics and composition
IAL-System Duo is a drug in the form of a transparent monophasic gel with a dense viscous consistency. It contains 75% stabilized hyaluronic acid BDDE and 25% HA ester ACP. One component gives a quick biostimulating effect, the second maintains the volume and elasticity of the skin for 6 - 8 months.
A small percentage of BDDE (less than 0.2 ppm) guarantees the composition is hypoallergenic and safe. The level of bacterial endotoxin is also low (less than 0.02 EU/mg). The pH ranges from 5 to 7. The total HA content is 25 mg/ml.
The package includes:
- 1 ml syringe filled with sterile gel
- Cannula 25 G
- Disposable needles (2 pcs.) in individual blister packs
- Puncture needle
Using Ial System ACP and Ial System in the same procedure
The essence of the combination is the simultaneous use of two drugs, which makes it possible to use each drug in the area where it is especially needed. Ial System ACP is injected into the area around the eyes, 3-4 mm away from the ciliary edge, using microinjections using the “point by point” technique. The same technique is used on the upper eyelid. The area around the eyes is characterized by swelling, which is not a contraindication to this drug. Ial System ACP is also recommended to be administered to seborrheic areas, as it significantly reduces sebum secretion. It stimulates collagen synthesis more actively and remains in tissues longer, and the clinical effect lasts 4-6 months. All other areas are treated with the Ial System, including the neck and décolleté area. The biorevitalization procedure using two drugs is carried out once a month. The number of procedures for an intensive course ranges from 2 to 4, depending on the individual characteristics of the skin, age and maintenance of the menstrual cycle.
Maximum stimulation of fibroblasts after biorevitalization is observed from 5 to 14 days. Fibroblasts are hormone-dependent skin cells, and their activity is directly related to the concentration of estrogen during the menstrual cycle in women. The maximum level of estrogen is observed on days 12-14 of the cycle. The combination can be considered optimal when the 5th day after the biorevitalization procedure corresponds to the 12-14th day of the menstrual cycle. That is, you can achieve maximum stimulation of fibroblasts by performing the biorevitalization procedure on days 7-9 of the menstrual cycle. This is especially true for premenopausal women, i.e. during the initial period of decreased ovarian function. Endocrinologically, this period is characterized by a decrease in estrogen concentration, and clinically by a change in the interval between menstrual cycles. Premenopause begins at the age of 42-45 years, its duration is from 2 to 10 years.
Indications
- Dry skin.
- Finely wrinkled skin
- Age-related changes.
- Dehydrated, dull skin
- Gray skin color
- Recovery after aggressive procedures, such as Fraxel
- Prevention of photoaging (2 weeks before the sea and two weeks after sunbathing)
- Hyperpigmentation
As for side effects, very rarely minor swelling or redness appears in the areas of drug administration due to dilation of the dermal vessels. The phenomena pass quite quickly. Sometimes hematomas occur at the injection sites. After 3-4 days, no traces of the bruises remain.
Combination of biorevitalization with other methods
1. Biorevitalization with Ial System / Ial System and Ial System ACP drugs goes well with superficial chemical peeling. After biorevitalization with Ial System 1.1, a chemical peeling procedure is performed on the 10th day. Exposure time and drug concentration are selected individually. On the 5th day after it, if the optimal level of moisture is achieved, biorevitalization is carried out with the drug Ial-System ACP. On the 10th day, chemical peeling is repeated, on the 5th day after it, the Ial System ACP procedure is performed, after 10-14 days, chemical peeling again. This combination allows you to normalize the synthesis of hyaluronic acid and collagen in the dermis, remove hyperkeratosis, pigmentation, and reduce the depth of wrinkles.
2. Biorevitalization and laser facial rejuvenation. After the fractional laser rejuvenation procedure, biorevitalization is carried out on the 14th day in order to restore the water balance of the dermis, necessary for cell division and differentiation. The use of biorevitalization allows you to shorten the rehabilitation period and get excellent results in the shortest possible time.
3. Biorevitalization and photorejuvenation potentiate each other’s action. The interval between these procedures should be 10 days. In case of rosacea, it is advisable to complete the program with a photorejuvenation procedure.
A universal treatment regimen for age-related skin changes
- Pre-peeling preparation in combination with biorevitalization.
- Peeling.
- Post-peeling rehabilitation in combination with biorevitalization.
- Botulinum toxin.
- Contour plastic.
Recommendations for skin care after the biorevitalization procedure
- During the first 24 hours after the procedure, it is not recommended to apply cosmetics and makeup; the use of the drug “Curiosin” and “Traumeel S” is allowed.
- Postpone visiting the solarium for 10-14 days, saunas and steam baths - for a week.
Contraindications to the Ial System biorevitalization procedure
- hypersensitivity to hyaluronic acid;
- pregnancy and lactation;
- active inflammatory process in the treatment area of any origin;
- tendency to form hypertrophic and keloid scars;
- taking blood thinning medications (aspirin, heparin, etc.);
- severe somatic diseases (diabetes mellitus, autoimmune processes, crisis course of hypertension, etc.);
- previously introduced synthetic implants in the treatment area.
Due to the high risk of post-inflammatory hyperpigmentation, it is not recommended to carry out the procedure earlier than 2 weeks after returning from active sun.
Indications for use
Lack of subcutaneous fat causes hypovolumia of the face and body. This leads to loss of contours and volume deficit in various areas. The action of IAL-System DUO is aimed at solving these problems; changes are noticeable immediately after the procedure. A soft elastic gel evens out the relief and replenishes volume. It is evenly distributed in the subcutaneous space, without irregularities and bumps.
The injection solves the following problems:
- smoothes nasolabial folds and eyebrow wrinkles;
- stops the aging of the skin of the hands;
- increases lip volume;
- aligns the oval of the face in the chin and cheek-zygomatic area.
What happens to the body after biorevitalization
Once in the body, hyaluronic acid
quickly begins to attract liquid and moisturizes the skin layers.
But replacement therapy is not the only effect of hyaluronic acid. It stimulates cellular processes, due to which the production of own HA is resumed, collagenogenesis and elastin production are normalized. And antioxidant activity
against free radicals accumulated in the body with age increases the effectiveness of the fight against aging.
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Efficiency and advantage of the method
Biorevitalization of facial skin in Moscow today is a very popular procedure. Its effectiveness has been proven by numerous positive reviews. The result is noticeable the day after the injections, when the papules from the injections disappear. Innovative drugs create a prolonged effect that increases over time, due to the normalization of metabolic processes and the acceleration of regeneration, and lasts on average about a year.
Advantages of the technique:
- safety: with the right choice of product and its professional administration, the risk of complications is minimal;
- painlessness: the injection needle has a very thin cross-section. Its introduction into the patient’s skin is practically not felt;
- long-term effect: depending on the chosen drug, the duration of the result is from 6 months to 1 year. The effect can be prolonged by carrying out preventive injections;
- instant results: tone improves, wrinkles smooth out, skin becomes radiant, fresh, moisturized and tightened.
Indications and contraindications for skin biorevitalization
Biorevitalization of facial skin in Moscow, according to experts, can cope not only with the signs of age-related decline of the dermis. It effectively regenerates the skin after unsuccessful peelings, sunburn, diseases that have left their mark in the form of scars and pits, etc. This is the best way to restore the structure of the dermal layers, strengthen its protective mechanisms and rejuvenate. The main indications are
:
- natural skin aging;
- decreased elasticity and turgor;
- consequences of injuries and unsuccessful operations, sudden weight loss (scars, scars, stretch marks);
- spider veins;
- dry, insufficiently moisturized skin;
- dark spots;
- skin disorders after ultraviolet burns and acne;
- enlarged pores;
- swelling, dark circles around the eyes;
- changing the oval of the face;
- uneven skin texture;
- small expression wrinkles.
Skin biorevitalization is recommended to be carried out before aesthetic surgeries. It is often combined with other cosmetic procedures, which significantly enhances their results. The procedure is recommended for use from 30 to 35 years old. In some cases, it can be carried out at an earlier age.
There are several contraindications
:
- pregnancy;
- breastfeeding period;
- cancer;
- autoimmune pathologies;
- tendency of the dermis to scar;
- individual intolerance to the drugs used.
In some conditions, such as acute respiratory infections, exacerbation of some chronic pathologies, menstruation, the presence of injuries and damage to the skin in the intended treatment area, the cosmetologist may temporarily (until the condition normalizes) remove you from the manipulation.
Advantages
Biorevitalization replenishes the reserves of hyaluronic acid in the skin. The lack of this substance explains aging and a decrease in skin thickness. Exposure to aggressive external factors negatively affects the protective potential of tissues. As a result, wrinkles, sagging and other defects appear.
The gold standard of biorevitalization IAL-System is based on 3 components. The first of these is efficiency. The drug triggers the division of connective tissue cells and helps restore blood microcirculation. In fact, a unique product activates natural rejuvenation processes.
The second and third components of the standard are safety and synergy. The drug does not include protein residues, which reduces the likelihood of allergies to zero. The combination (synergy) of several products at once (IAL-System and IAL-System ACP) significantly increases the shelf life of the effect.
Although IAL biorevitalization is not an alternative to plastic surgery, the procedure speeds up postoperative rehabilitation. If “youth injections” are given shortly before surgery, tissues heal faster and hematomas disappear. Saturation with useful substances helps to better tolerate recovery.
In addition to the face, biorevitalizants are injected into the hands, neck, knees, elbows, buttocks, armpits and décolleté. The listed zones are a kind of indicators of aging. Therefore, their correction gives amazing results. Finally, biorevitalization can be combined with peelings and hardware correction of appearance.
