Profhilo / PROFHILO – new facets of biorevitalization

Expert tested
Natalya Borisovna Zhmurina Director, Chief Physician of “A Clinic” Dermatovenereologist, cosmetologist

Publication date: February 13, 2022

Review date: November 10, 2022

Profhilo is an innovative product from the leader in the production of hyaluronic acid-based products - the IBSA company. IBSA was founded in Switzerland in 1945. Now its representative offices operate in Europe, the USA, and China. The company is a recognized expert in hyaluronic acid. It produces ultra-pure hyaluronic acid, obtained through a bacterial fermentation process and classified as "Top Quality".

Since sales began in Italy in February 2015 and launched internationally in January 2016, Profhilo has won three awards:

  1. International award in the field of aesthetic medicine in the category Skin Enhancement Anti-Aging Beauty Trophy 2015-2016
  2. Aesthetic Awards for Product Innovation of the Year 2016
  3. International Congress on Anti-Aging Medicine - AMEC and Aesthetics Awards 2022 as the best injectable product of the year

What is Profilo?

This is the world's first drug that combines both lifting and moisturizing effects.
This synergy is called Hydrolift.
The drug is based on hyaluronic acid with low and high molecular weight in equal proportions. This is a special hybrid technology developed and patented by IBSA scientists.

Low molecular weight hyaluronic acid moisturizes the skin and gives a reinforcing effect.

High molecular weight – improves local blood circulation, stimulates the production of your own collagen, and provides tissue lifting. This is achieved due to the accumulation of water molecules around the high molecular weight acid.

In general, Profhilo activates the vital activity of not only fibroblasts and keratinocytes, but also adipocytes (fat cells), supports their viability, which leads to the restoration of its own subcutaneous fat, the deficiency of which is determined with age.

Profilo allows you to achieve an easy, dynamic increase in soft tissue volume and an impressive improvement in skin quality. After administration of the drug, the skin quickly recovers, the risk of inflammation and complications is reduced to zero.

Avdeyuk Elena Vladimirovna

Dermatovenerologist, cosmetologist

High fluidity allows the components of the drug to freely pass through the subcutaneous tissue and dermis, which is not possible with traditional fillers with hyaluronic acid. Profhilo is ideal for introducing into anatomically complex areas that were previously difficult to give volume to: the forehead, neck, submandibular areas.

Recommendations for the procedure

Injections of the drug are recommended for patients who:

  • loose, dry skin;
  • pronounced age-related, facial wrinkles;
  • scars and post-acne;
  • dark spots.

Profhilo effectively eliminates wrinkles even in anatomically complex areas: on the forehead, neck, under the jaw. Injections are prescribed during the period of preparation for plastic surgery and after surgery. There are no contraindications to the procedure or age restrictions. The product is recommended for patients aged 25 to 75 years.

How to enter Profile

The unique formula of the drug made it possible to develop new protocols for its administration. First of all, the number of required injection points has been reduced. For the face, the “5 BET” technique is used - 5 bioaesthetic points for each side of the face. Five points correspond to five areas of the face, selected taking into account the anatomical structure: there are no large vessels or nerve endings there. Thanks to this, the risks of side effects are minimized, and maximum distribution of the drug in the cheekbones and lower jaw is achieved.

In the neck area, the drug is injected into 10 bioaesthetic points. They are also located taking into account the existing anatomical structures and do not affect such important organs as the submandibular salivary glands and the thyroid gland, the carotid artery, the trachea and the larynx.

Advantages of PROFHILO fillers

The advantages of the drug include:

  1. Instant results with longer lasting effects (up to 8-12 months).
  2. Fewer injection points.
  3. No pain, no swelling and no bruising.
  4. Does not require preliminary anesthesia.

Result:

  • Instant tightening and tightening of the skin of the face, arms, neck, décolleté, and body.
  • Elimination of fine wrinkles.
  • Moisturizing and rejuvenating the lip area.
  • Elimination of atrophic scars on the face and body.

The PRESIDENTMED clinic offers effective procedures aimed at rejuvenation and elimination of cosmetic defects and imperfections.

Our specialists will help you cope with age-related changes and restore your skin to its flawless appearance.

The effective technique of the PRESIDENTMED clinic is to use the drug “PROFHILO” without complications and associated risks.

What results can you achieve with Profhilo?

Remodel the contours of the face and correct the cheekbone area (create the effect of beautiful high cheekbones) Restore the subcutaneous tissue, increasing its volume Restore the clarity of the contour of the lower jaw Rejuvenate the tissues of the neck and décolleté Give the skin radiance

Why PRESIDENTMED?

  • This is the leading medical institution in the Russian Federation, using only certified and safe treatment methods!
  • This is a center of excellence for training specialists in hardware methods!
  • These are highly qualified specialists, professors, candidates of science, world-famous doctors!
  • this is the introduction of new methods of diagnosis, treatment and the use of “last word” technologies in medicine!

Our clinic employs only experienced specialists who are constantly trained in the latest cosmetology methods. The clinic is also the largest specialist training center in the Russian Federation.

PROFHILO fillers at the PRESIDENTMED clinic mean freshness and youthfulness of your skin for a long time.

Gel Collost contraindications:

  • Positive test sample;
  • Autoimmune diseases;
  • Severe somatic diseases;
  • Oncological diseases;
  • Pregnancy and lactation;

To correct age-related changes, the procedure is indicated for people over 30 years of age. To resolve aesthetic issues - after 18-20 years.

Collostotherapy is a technique that allows you to restore the tone, elasticity and color inherent in young and healthy skin, and protect it from the effects of free radicals. Deep regenerative therapy provides the cellular microenvironment characteristic of young skin, slowing down aging. Thus, this method can rightfully be considered an alternative to plastic surgery.

Uniqueness in comparison with classical biorevitalization

Compared to traditional biorevitalization of sagging skin, bioremodeling has the following advantages:

  • fewer punctures during procedures;
  • better obvious result with longer lasting effect;
  • a minimum number of procedures to ensure the durability of the achieved result.

For painless administration and maximum effectiveness of the drug in patients with various conditions of the skin and the whole body, five biologically active points on each side of the face. Their choice determines the further absence of papules and hematomas as side effects of the procedure. This injection system was called the “bioaesthetic point technique” (BET) and was developed specifically for the drug PROFHILO/Profilo.

The drug Profhilo is administered slowly to avoid sudden stretching of tissues and, as a result, pain. For its uniform distribution, 24–48 hours are enough. Each targeted injection of a small dose of PROFHILO/Profilo restores and remodels the epidermis with a diameter of 4 cm for a long period due to deep saturation with hyaluronic acid.

The basic course is limited to only two procedures with an interval of one month . Additional correction, if necessary, is possible after 2-3 months.

Comparative illustration of different types of biorevitalization

Scar treatment

Scars occur as a result of wound healing.

A scar is a product of regeneration (restoration) of damaged skin.

It is newly formed connective tissue at the site of damage to the skin and deeper tissues.

Highlight:

  • Normotrophic (physiological) scars
  • Atrophic
  • Hypertrophic
  • Keloid

Normotrophic (physiological) scars after 3-6 months become thin, whitish in color, and do not cause physical discomfort to a person. These scars usually do not need correction. The exception is cases of aesthetic improvement of the appearance of the scar, smoothing the surface or accelerating the rate of color normalization.

With atrophic scars, the skin over the scar is flabby, has transverse striations; often such scars are devoid of pigment, so they look white. The characteristic appearance of these scars is due to a defect in the connective tissue under the scar, a deficiency of collagen and elastin, the main proteins that form the framework of the skin.

Hypertrophic scars rise above the surface of the skin, they are mobile, painless, and have a soft consistency. Localization: cheeks, nasolabial folds, around the mouth, anterior, posterior and lateral surfaces of the neck, sternum.

Hypertrophic scars, like keloid scars, rise above the surrounding skin, but, unlike keloid scars, they occupy an area corresponding to the previous damage.

Keloid scars belong to the group of pseudotumor skin diseases. This is a dense, lumpy growth of connective tissue with a smooth shiny surface and a color from pink to bluish-purple.

There is often tingling, burning, itching, and pain.

Characterized by the ability to constantly grow and relapse after treatment.

What is the drug used for?

Provides an amazing effect of contouring and simultaneous biorevitalization .

Fights skin flabbiness: not only moisturizes the skin in all layers, but also remodels it, enhances regeneration processes, and supports the protective functions of the skin.

Low molecular weight HA “works” at the cellular level, restoring elasticity from the inside, while high molecular weight provides a lifting effect.

Distinctive features of the drug:

  1. Increased concentration of hyaluronic acid in each syringe - 64 mg (32 mg/ml).
  2. Optimal balance of high and low molecular weight hyaluronic acid without additional binding elements (pure HA).
  3. Patented system for administering the drug without papules (!!!).
  4. Activation of the vital activity of fibroblasts.

The thoroughly purified hyaluronic acid in PROFHILO® does not contain cross-linking agents, i.e. impurities of foreign chemical components. This reduces the risk of allergic reactions and side effects.

Treatment of stretch marks (striae).

Stretch marks (or stretch marks, as experts call them) are shallow scars in the form of wavy stripes that appear in places where the skin is chronically stretched. Most often they appear during pregnancy, puberty, with some endocrine diseases, as well as with a sharp change in body weight. Stretch marks can form on the abdomen, on the hips and buttocks, on the chest, and in case of endocrine problems, on the face. As a result of overextension or hormonal changes, the skin becomes thinner and loses elasticity, which leads to internal micro-tears, which are later replaced by connective tissue. Essentially, scar tissue forms at the site of healing of micro-tears in collagen and elastin fibers. There is no pigment in scar tissue, so stretch marks remain white when tanned and become more visible against tanned skin.

Until recently, the most common method for correcting stretch marks was resurfacing. When sanding, the surface layers of the skin are removed and the impression of smoothing is created. As a result, stretch marks become slightly less noticeable, but the problem cannot be completely solved, since the normal tissue structure in the areas of stretch marks is not restored.

In recent years, the use of the Collostotherapy method has allowed us to take a fresh look at the difficult task of correcting stretch marks and significantly improve treatment results.

What affects the cost of the procedure at the Doctor Grishkyan clinic in Moscow

The cost of Profhilo injections in a specialized clinic in Moscow depends on the status and level of the institution, the experience and qualifications of specialists, and the number of courses required. The specialist determines the number of sessions individually in each specific case - it depends on the condition of the patient’s skin. To eliminate pronounced age-related changes, several sessions may be required at intervals of one to two months.

Biorevitalization

Procedure namePrices
NCTF 135 3ml7000
NCTF 135 HA+ 3ml15000
M-HA 18 1ml18000
Novacutan S-BIO 2ml14000
Novacutan Y-BIO 2ml14000
Melsmon 2ml6000
PROFHILO19000
Juviderm HYDRATE 1 ml14000
Juviderm VOLITE 1 ml22500
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